Schedule – Advanced Genetics - PCB 5065 - Fall 2007

Section 2191, MTWR 5th Period, 2318 Fifield Hall

Date

Instructor

Topic

Thurs

Aug 23

All

Introduction and course introduction

 

 

 

 

Mon

Aug 27

Hannah

The gene in molecular terms

Tues

Aug 28

Hannah

The gene pre-Mendel to Mendel

Wed

Aug 29

Hannah

The gene as a unit of function

Thurs

Aug 30

Hannah

The gene as a unit of mutation

 

 

 

 

Mon

Sept 3

Labor Day

Holiday - No Class

Tues

Sept 4

Hannah

The rII cistron of phage T4 - running the gene into the ground

Wed

Sept 5

Hannah

The gene and the operon

Thurs

Sept 6

Hannah

Allelic interactions, cistrons and operons - was Mendel wrong?; Genic interactions - epistasis

 

 

 

 

Mon

Sept 10

Hannah

Transposable elements I - molecular and genetic properties

Tues

Sept 11

Hannah

Transposable elements II - tools of forward and reverse genetics

Wed

Sept 12

Hannah

Forward and reverse genetics - further approaches

Thurs

Sept 13

Chase /  Hannah

Discussion paper on genes, mutations and transposons

 

 

 

 

Week of  Sept 17

Hannah

2 hr evening exam on genes, mutations and transposons

Mon

Sept 17

Gabriel

Segregation, assortment, chromosome mechanics, nondisjunction

Tues

Sept 18

Gabriel

Genes & chromosomes

Wed

Sept 19

Gabriel

Linkage, gene order, linearity, crossing-over, recombination

Thurs

Sept 20

Gabriel

Tetrad analysis & sister-strand exchange

 

 

 

 

Mon

Sept 24

Gabriel

Mechanisms of crossing over - gene conversion & Holiday structures

Tues

Sept 25

Gabriel

Mechanisms of crossing over - Messelson-Radding  & gene conversion

Wed

Sept 26

Gabriel

Mechanisms of crossing over - Double strand break repair model

Thurs

Sept 27

Gabriel

Mechanisms of crossing over - Parasexuality and mitotic recombination  

 

 

 

 

Mon

Oct 1

Gabriel

Site-specific recombination systems

Tues

Oct 2

Chase

Discussion paper on recombination

Wed

Oct 3

Gabriel

Review

Thurs

Oct 4

Gabriel

No Class/evening exam

 

 

 

 

Mon

Oct 8

Chase/Moore

Genome organization

Tues

Oct 9

Chase/Moore

Molecular markers

Wed

Oct 10

Chase/Moore

Linkage mapping

Thurs

Oct 11

Chase/Moore

Physical mapping

 

 

 

 

Mon

Oct 15

Chase/Moore

Positional cloning

Tues

Oct 16

Chase/Moore

Chromosome structure

Wed

Oct 17

Chase/Moore

Chromosome variation

Thurs   

Oct 18

Chase

Discussion paper on genomes, maps & chromosomes

 

 

 

 

Week of Oct 22

Moore

2 hr evening exam on genomes, chromosomes, and mapping

Monday

Oct 22

Chase/McCarty

Non-Mendelian inheritance - organelle inheritance I

Tues   

Oct 23

Chase

Non-Mendelian inheritance - organelle inheritance II

Wed

Oct 24

Chase

Non-Mendelian inheritance - maternal effects, cytoplasmic microorganisms, meiotic drive

Thurs

Oct 25

Chase

Non-Mendelian inheritance - epigenetics

 

 

 

 

Mon    

Oct 29

Chase

Non-Mendelian inheritance - epigenetics

Tues

Oct 30

McCarty

Developmental genetics - general concepts

Wed

Oct 31

McCarty

Developmental genetics – drosophila I

Thurs

Nov 1

McCarty

Developmental genetics – drosophila II

 

 

 

 

Mon

Nov 5

McCarty

Developmental genetics – plants I

Tues

Nov 6

McCarty

Developmental genetics – plants II

Wed

Nov 7

Chase

Discussion paper on non-Mendelian and developmental genetics

Note FL Genetics Symposium 1-5 today; CGRC 101 & 133

Thurs

Nov 8

NO CLASS

FL Genetics Symposium 8-5 today; CGRC 101 & 133 

 

 

 

 

Week of Nov 12

 Chase  

  2 hr evening exam on non-Mendelian and developmental genetics

Mon

Nov 12

NO CLASS

Veterans Day Holiday

Tues

Nov 13

Wu

Population genetics - population structure

Wed

Nov 14

Wu

Population genetics - Hardy-Weinberg equilibrium

Thurs

Nov 15

Wu

Population genetics - effective population size

 

 

 

 

Mon

Nov 19

Wu

Population genetics - linkage disequilibrium

Tues

Nov 20

Wu

Population genetics - evolutionary forces

Wed

Nov 21

Wu

Genetic Parameters: Means

Thurs

Nov 22

NO CLASS

Thanksgiving Holiday

 

 

 

 

Mon

Nov  26

Wu

Genetic Parameters: (Co)Variances

Tues

Nov 27

Wu

Mating Designs for Parameter Estimation

Wed

Nov 28

Wu

Experimental Designs for Parameter Estimation

Thurs

Nov 29

Wu

Heritability, Genetic Correlation and Gain from Selection

 

 

 

 

Mon

Dec 3

Chase

Take-home instructor evaluations given

Mon

Dec 3

Wu

Molecular Dissection of Quantitative Variation – Linkage Analysis

Tues

Dec 4

Wu

Molecular Dissection of Quantitative Variation – Association studies

Wed

Dec 5

Chase/Wu

Discussion paper on population and quantitative genetics

Wed

Dec 5

Chase

Take-home instructor evaluations due

Wed

Dec 5

Wu

Take-home exam on population and quantitative genetics given- due in electronic format (rwu@ifas.ufl.edu) by 5 PM Tuesday Dec 11 

Thurs

Dec 6

Reading Day - No class

 



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