The 14-3-3's

Protein Alignment Arabidopsis Genes Reviews




     Welcome to the 14-3-3 web page at the University of Florida!  Here you will find the most current information concerning Arabidopsis thaliana 14-3-3's.  Links to specific information about 14-3-3s can be obtained by clicking on the isoform name on the image map above. 


A Brief History of 14-3-3s

The 14-3-3 proteins were initially discovered in 1967 by Moore and Perez during an extensive study of bovine brain proteins. The 14-3-3 proteins were given numerical designations based on column fractionation and electrophoretic mobility. They are currently designated as Greek letters. The 14-3-3s are a family of acidic, soluble proteins with a native size of 30 kDa. Initially this protein family was thought to be limited to mammalian nervous tissue.  However, 14-3-3s are currently considered to be ubiquitous. Their presence has been identified in virtually every eukaryotic organism and tissue. 


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Copyright 2006 Robert J. Ferl Laboratory, University of Florida
Last modified: 03/01/06